APP 669-711, HCl

Product background: Amyloid Precursor Protein (APP) is a membrane spanning protein that functions as the precursor to Amyloid-Beta in plaques of Alzheimer’s Disease patients. The extra cellular region is proteolytically cleaved to release amyloid peptides.

About the product: Expressed recombinantly in E. coli, APP 669-711 is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.

Applications: The HCl counter-ion is lyophilized in an acidic environment, which some consider to be more physiologically relevant and less toxic. It also ensures a highly monomeric starting material that may be suited to aggregation studies, seeding experiments, molecular standards and more.